Yopo is a traditional psychedelic and medicinal snuff made from the seeds of the *Anadenanthera peregrina* tree; it is used in Indigenous ceremonies for healing and spiritual connection. The term "activated" typically refers to the process of mixing and preparing the powdered seeds with alkaline substances (such as plant ash or snail shell powder) to release their active compounds.

Main uses of yopo

Spiritual connection:

Shamans use it to enter altered states of consciousness and communicate with the spiritual world. Healing and diagnosis: It allows traditional healers to receive guidance for curing illnesses or expelling ailments from the patient's body.

Mental clarity: It is believed to provide clarity of thought and help individuals endure extreme physical conditions during rituals.